What is the recommended dose of midazolam when used with ketamine, for non-intubated patients?

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The correct dosage of midazolam when used in conjunction with ketamine for non-intubated patients is 0.5-2 mg every 5 minutes. This range is established based on the need to achieve sedation while ensuring patient safety and minimizing risks associated with respiratory depression and other side effects.

Midazolam is a benzodiazepine that provides anxiolytic and sedative properties, and when used with ketamine—a dissociative anesthetic—the combination can enhance sedation effectively. The specified dosage allows for titration based on the patient's response, catering to the individual needs without over-sedating the patient, which is critical in non-intubated individuals who still have the capacity to maintain their own airway.

Using higher doses or more frequent administration, such as those found in other choices, could increase the risk of complications like respiratory depression or prolonged sedation, potentially leading to adverse outcomes. Therefore, the recommended dose emphasizes safety while effectively managing sedation.

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